Archives

  • 2019-07
  • 2019-08
  • 2019-09
  • 2019-10
  • 2019-11
  • 2020-03
  • 2020-07
  • 2020-08
  • 2021-03
  • br Our findings indicate that tomosynthesis e

    2020-07-04


    Our findings indicate that tomosynthesis e at least for the cur-rent version of the technology e does not improve the measure-ment of BC size relative to standard mammography, when cancers are seen on both tests. Tomosynthesis detects additional, mammographically-occult lesions in the screening setting, but measurement variability is large, and hence clinicians should be aware of the possibility of inaccurate measurement by tomosyn-thesis in those women. Given that the number of cancers detected only by tomosynthesis was modest, our finding of relatively inac-curate measurement in that group requires further exploration in larger studies, and should be interpreted in the context that tomosynthesis-only detection of BC was frequently in dense breasts  which also limits cancer size measurement.
    Funding
    This work was supported by a Cancer Institute NSW (CINSW) Early Career Fellowship, Grant ID No. 14/ECF/1-06 (ML Marinovich), and by a National Breast Cancer Foundation (NBCF Australia) Breast Cancer Research Leadership Fellowship (N Houssami).
    The study sponsors had no role in the study design, collection, analysis and interpretation of data; in the writing of the manu-script; and in the decision to submit the manuscript for publication.
    Conflicts of interest
    All authors declare no conflicts of interest.
    Appendix A. Supplementary data
    References
    [1] Houssami N, Skaane P. Overview of the evidence on digital breast tomosyn-thesis in breast cancer detection. [Review]. Breast 2013;22:101e8. [2] Svahn TM, Houssami N, Sechopoulos I, Mattsson S. Review of radiation dose estimates in digital breast tomosynthesis relative to those in two-view full-field digital mammography. [Review]. Breast 2015;24:93e9. [3] Ciatto S, Houssami N, Bernardi D, et al. Integration of 3D digital mammog-raphy with tomosynthesis for A 61603 breast-cancer screening (STORM): a prospective comparison study. Lancet Oncol 2013;14:583e9.
    [4] Skaane P, Bandos AI, Gullien R, et al. Comparison of digital mammography alone and digital mammography plus tomosynthesis in a population-based screening program. Radiology 2013;267:47e56.
    [5] Bernardi D, Macaskill P, Pellegrini M, et al. Breast cancer screening with tomosynthesis (3D mammography) with acquired or synthetic 2D mammography compared with 2D mammography alone (STORM-2): a allergens population-based prospective study. Lancet Oncol 2016;2016:2016. Date of Publication: 2016.
    [6] Houssami N, Turner RM. Rapid review: estimates of incremental breast cancer detection from tomosynthesis (3D-mammography) screening in women with dense breasts. Breast 2016;30:01. [7] Senkus E, Kyriakides S, Ohno S, et al. Primary breast cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 2015;26:mdv298.
    [8] Fornvik D, Zackrisson S, Ljungberg O, et al. Breast tomosynthesis: accuracy of tumor measurement compared with digital mammography and ultrasonog-raphy. Acta Radiol 2010;51:240e7.
    [9] Seo N, Kim HH, Shin HJ, et al. Digital breast tomosynthesis versus full-field digital mammography: comparison of the accuracy of lesion measurement and characterization using specimens. Acta Radiol 2014;55:661e7. [10] Destounis SV, Arieno AL, Morgan RC. Preliminary clinical experience with digital breast tomosynthesis in the visualization of breast microcalcifications. J Clin Imag Sci 2013;3:65. [11] Marinovich ML, Macaskill P, Irwig L, et al. Meta-analysis of agreement be-tween MRI and pathologic breast tumour size after neoadjuvant chemo-therapy. Br J Canc 2013;109:17. [12] Meacock LM, Mombelloni AI, Iqbal A, Akbar N, Wang Y, Michell MJ. The ac-curacy of breast cancer size measurement: digital breast tomosynthesis (DBT) vs 2D digital mammography (DM). Insights Imagin 2010;1:S306. [13] Bland JM, Altman DG. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986;1:1986. [14] Marinovich ML, Macaskill P, Bernardi D, et al. Systematic review of agreement between tomosynthesis and pathologic tumor size for newly diagnosed breast cancer and comparison with other imaging tests. Expet Rev Med Dev 2018;15(7):489e96.
    [15] Bland JM, Altman DG. Measuring agreement in method comparison studies. Stat Methods Med Res 1999;8:1999. [16] Woodward M. Basic analytic procedures. Epidemiology: study design and data
    [17] Marinovich ML, Hunter KE, Macaskill P, et al. Breast cancer screening using tomosynthesis or mammography: a meta-analysis of cancer detection and recall. J Natl Cancer Inst 2018;110(9):942e9. [18] Gilbert FJ, Tucker L, Young KC. Digital breast tomosynthesis (DBT): a review of the evidence for use as a screening tool. Clin Radiol 2016;71(2):141e50.