• br progression The constitutive activation of STAT in TNBC

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  progression [15]. The constitutive activation of STAT3 in TNBC is as-sociated with drug resistance to chemotherapy and a shorter survival period [16,17]. Blockage of the JAK/STAT axis elicits anti-angiogenic and -metastatic effects via suppression of the downstream signaling pathways involved [18–

• br Fig Genotype distribution and allele frequency of rs

  2022-08-11

  

  Fig. 3. Genotype distribution and allele frequency of rs4646903 of gene CYP1A1 in world ethnic groups from NCBI. Genotype distribution and allele frequency of the study was compared with the data of other ethnic groups from the NCBI database; for rs4646903 the Ac-DEVD-CHO was similar with Afri

• br Declaration of Competing Interest br The authors

  2022-08-11

  

  Declaration of Competing Interest “The authors declare no potential conflicts of interest”. Acknowledgements References Bubnovskaya, L., Kovelskaya, A., Gumenyuk, L., Ganusevich, I., Mamontova, L., Mikhailenko, V., Osinsky, D., Merentsev, S., Osinsky, S., 2014. Disseminated tumor Conca

• ATPγS birads mass Normal br Properties of each feature

  2022-08-11

  

  75 birads5-mass 49 Normal 41 Properties of each feature extractor applied to the datasets. Feature extractor Category #Features In order to corroborate the generalization and enable the repli-cation of our approach, we used public medical image datasets de-  scribed in Section 3.

• inhibited by BPA Tyr and Tyr BPA suggesting that

  2022-07-28

  

   inhibited by BPA-Tyr and Tyr-BPA, suggesting that they are trans-ported by intrinsic tumor cell PEPT1. The incorporation of BPA-Tyr and Tyr-BPA into tumor ATP by PEPT1 was confirmed by siRNA-mediated knockdown in AsPC-1 cells. AsPC-1 cell line was chosen because it was used in a previous stud

• br Table br Physicochemical parameters of bombesin conjugated EGCG loaded

  2022-07-26

  

  Table 1 Physicochemical parameters of bombesin conjugated, EGCG-loaded solid lipid nanoparticles (EB-SLN). Properties Values R. Radhakrishnan, et al. Fig. 1. Percent cell viability of MDA-MB-231 human breast cancer Nivolumab after 48 h of treatment with pure EGCG, EGCG-loaded SLN (EG

• br The adjuvant treatment was very homogeneous

  2022-07-26

  

  The adjuvant treatment was very homogeneous across subgroups. One hundred and thirty-five (56.4%) patients received a sequential chemotherapy with anthracyclines and taxanes. Seventy-eight (32.6%) received only anthracyclines and 26 (10.8%) taxanes alone. All patients completed the adjuvant chemot

• br To quantify the phototherapeutic e

  2022-07-26

  

  To quantify the phototherapeutic effect of BP/DACHPt, the MTT assay was conducted to determine the viability of HeLa cells. Firstly, the cytotoxicity of freshly prepared bare BP was test in four different cell lines, including three cancer cell lines and one normal cell line (HeLa, HepG2, A549 and N

• br We found that ERK mediated

  2022-07-26

  

  We found that ERK1/2 mediated activation of TGF-β/Smad2/3 signals was involved in BPS induced migration of NSCLC cells. TGF-β/ Smad2/3 signals have been well illustrated to regulate the development of NSCLC via promoting cancer cell motility, invasiveness and metas-tasis (Moustakas and Heldin, 200

• br Nanomedicines are a diverse collection

  2022-07-25

  

  Nanomedicines are a diverse collection of nanoscale materials measuring approximately 5-150 nm in mean diameter. These include therapeutic, diagnostic, and theranostic compounds (which are simultaneously therapeutic and diagnostic). Most clinically-approved nanomedicines for oncology are macromole

• DMAPP M Bilal T Rasheed H Iqbal H Hu

  2022-07-25

  

  [19] M. Bilal, T. Rasheed, H. Iqbal, H. Hu, X. Zhang, Silver nanoparticles: biosynthesis and antimicrobial potentialities, Int. J. Pharmacol. 13 (2017) 832Ð845. [20] M.K. Patel, M. Zafaryab, M.M.A. Rizvi, V.V. Agrawal, Z.A. Ansari, B.D. Malhotra, S.G. Ansari, Antibacterial and cytotoxic effect of

• br References br M G Vander Heiden

  2022-07-25

  

  References [2] M.G. Vander Heiden, L.C. Cantley, C.B. Thompson, Understanding the Warburg effect: the metabolic requirements of cell proliferation, Science 324 (2009) clastogenesis inhibitor through the inhibition of glyoxalase I, Proc. Natl. Acad. Sci. Identification of a small-molecule i

• Wortmannin br N Arunkumar has completed in

  2022-07-06

  

  N. Arunkumar has completed in his BE, ME in Electronics and Communication Engineering with specialization in Biomedical Engineering. He has a strong academic teach-ing and research experience of more than 11 years in SASTRA University, India. He is appreciated for his in-novative research oriented

• br Autophagy and mitochondria in cancer cachexia br Fig

  2022-07-06

  

  Autophagy and mitochondria in cancer cachexia 2679 Fig. 4. TP53INP2 overexpression worsens tumor-induced muscle, though not adipose loss. Lean (a) and fat (c) % mass time course of controls (C) and C26-bearing mice (C26) either WT (n = 5 for C and 9 for C26) or overexpressing TP53INP2 specific

• br AS HJM AW made

  2022-06-21

  

  • AS, HJM, AW made substantial contributions to conception and design, acquisition of data, and analysis and interpretation of data; • HJM, AW been involved in drafting the manuscript or revising it critically for important intellectual content; • HJM, AW given final approval of the version

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