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A769662 br Primary tumour volume reduction during EBRT is
2020-08-30
Primary tumour volume reduction during EBRT is, and ADC in-crease during EBRT might be, a good predictor for regional and distant control; however their relation is not fully clarified. Perhaps it is the tumour biology of the primary tumours and the lymph node metastasis and their response to trea
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Cancer Letters br Sphere formation assay br Sphere culture w
2020-08-30
Cancer Letters 453 (2019) 158–169 2.4. Sphere formation assay Sphere culture was performed as previously described [24,25]. Briefly, Meropenem were plated in 24-well Ultra-Low Attachment Plates (Corning) with DMEM: F12 medium plus 2% B27 (Gibco) and 20 ng/ml bFGF (PeproTech). The culture m
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U-46619 br Materials and methods br
2020-08-30
Materials and methods Materials Caudatin (Purity: 98%) was purchased from Shenzhen Medherb Biotechnology Co., Ltd. (Shenzhen, China). The JNK Inhibitor SP600125 was purchased from Merck Chemicals (Darmstadt, Germany). The p38 MAPK inhibitor SB203580 was obtained from Santa Cruz Biotechnology
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br Table Mean radiation therapy doses
2020-08-28
Table 2 Mean radiation therapy doses to coronary arterial structures from left-sided breast cancer radiation therapy regimens used in Sweden (1958-2001) or Denmark (1978-2000) Radiation therapy regimen* Mean coronary artery doses (Gy)y Country Median Medial Border Field arrangementz,x
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br Other factors to consider
2020-08-28
Other factors to consider regarding adolescent vaccine ac-ceptance that may merit future study include the potential impacts of social media and peer pressure. Depending on the source and content of social media postings or the focus of direct or indirect peer pressure, substantial shifts in eithe
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br Interpretation We demonstrate that
2020-08-28
Interpretation: We demonstrate that BCF, as a single agent or in combination with radiation, is a novel treatment approach to the treatment of 36913-39-0 metastases. This paradigm shifting modality warrants further clinical trials for this unmet medical need. © 2019 The Authors. Published by E
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br cytochrome C release and intrinsic pathway
2020-08-28
cytochrome C release and intrinsic pathway activation, it also combined with Bcl-2 family proteins, resulting in activation of mitochondrial dysfunction, and then leading to caspase activation and cell death (Nakano et al., 2001). The induction of bax and bcl-2 was inhibited in buforin IIb treated
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br Because of the large age range in
2020-08-24
Because of the large age range in our study population, we cannot eliminate the possible influence of cohort effects. We controlled for age in our models and our analyses restricting subjects to women 50 + years of age produced findings similar to those of the overall popula-tion. In addition,
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br UCP is a mitochondrial protein that shares sequence homol
2020-08-18
UCP2 is a mitochondrial protein that shares 60% sequence homology with UCP1 (mainly expressed in brown adipose tissue), which produces heat by dissipating 944808-88-2 synthesis. Several studies have demonstrated that activation of UCP2 can reverse metabolic re-programming, leading to a return tow
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br Corresponding authors at IICT RMIT Research Centre CSIR I
2020-08-18
Corresponding authors at: IICT-RMIT Research Centre, CSIR-Indian Institute of Chemical Technology, Hyderabad, India. E-mail addresses: [email protected] (D. Pooja), [email protected] (S. Bhargava), [email protected] (S. Ramakrishna). R. Radhakrishnan, et al. used to incorpor
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br Taqman assay for Dusp
2020-08-18
Taqman assay for Dusp1 Life Technologies Taqman assay for Gapdh Life Technologies Taqman assay for Gclm Life Technologies Taqman assay for Hmox1 Life Technologies Taqman assay for Hk1 Life Technologies Taqman assay for Hk2 Life Technologies Taqman assay for Mmp1
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br Acknowledgments br References br HER FISH pharmDx Interpr
2020-08-18
Acknowledgments References HER2 FISH pharmDx. (2014). Interpretation guide—Breast cancer. Carpinteria, CADako: Dako manual. Hsu, W. Y. (2012). Improved watershed transform for tumor segmentation: Applica-tion to mammogram image compression. Expert Systems with Applications, 39(4), 3950–39
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br Fig Kaplan Meier plots showing A overall survival and
2020-08-18
Fig. 2. Kaplan-Meier plots showing (A) overall survival and (B) progression-free survival of patients with and without TP53 mutations from ICI initiation. NR: Not Reached. instability [30], thereby spurring tumor immunogenicity by generating tumor neo-antigens or resulting in mutations in domin
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br The authors declare that
2020-08-14
The authors declare that they have no conflict of interest to disclose. References Burkle, A., 2001. Poly(APD-ribosyl)ation, a DNA damage-driven protein modification and regulator of genomic instability. Cancer Lett. 163 (1), 1–5. Hassa, P.O., Hottiger, M.O., 2008. The diverse biological
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br Marinac CR Nelson SH
2020-08-14
[28] Marinac CR, Nelson SH, Breen CI, et al. Prolonged nightly fasting and breast cancer prognosis. JAMA Oncol 2016;2:1049e55. [29] Djiogue S, Nwabo Kamdje AH, Vecchio L, et al. Insulin resistance and cancer: the role of insulin and IGFs. Endocr Relat Cancer 2013;20:R1e17. [30] Brower KJ, Aldric